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The Best Ergonomic Mice to Save You From a Wrist Brace

Ergonomic mouse and normal computer mouse. Black vertical optical computer mouse with ergonomic design, designed to reduce injuries such as carpal tunnel syndrome, arthritis.
Nor Gal/Shutterstock.com

Repetitive use of a mouse and keyboard can strain your wrists and lead to carpal tunnel. But you aren’t doomed to wear a wrist brace just yet. You still have time to switch over to an ergonomic mouse, which minimizes wrist movement and helps to prevent injury over time.

Update, 4/7/22: Updated link for Logitech MX Vertical and Microsoft Sculpt combo. Add picks for gaming and left-handed users.

Before Buying an Ergonomic Mouse

Ergonomic mice come in all different shapes and sizes, but they’re all made to keep your wrist from twisting in nasty directions while working at the computer. Most ergonomic mice accomplish this by forcing your hand to sit in a position that’s level with your forearm and elbow.

Still, some ergonomic mice may be a little unconventional for your tastes. We’re going to look at a wide variety of ergonomic mouse designs in this article, but we should take a second to review different mouse shapes, features, and quirks to make shopping just a little bit easier.

  • Mouse Style: The ergonomic mice in this article come in three styles. Here’s a quick rundown:
    • Vertical: Vertical mice put your hand into a sideways, handshake position. They’re relatively easy to get used to and offer an unmatched level of ergonomics.
    • Traditional: Some traditional mice have a bulky design that keeps your wrist straight without compromising usability. They aren’t as effective as vertical or trackball mice, but they’re more ergonomic than a typical mouse.
    • Trackball: Trackballs aren’t nearly as popular as they used to be, but their bulky shape and stationery design are great for reducing wrist strain. These mice have a bit of a learning curve, but they’re more effective at reducing wrist strain than traditional mice.
  • Extra Buttons: Some modern mice have extra buttons for opening menus and moving back and forth in a browser tab. If you’re the kind of person who relies heavily on extra mouse buttons, keep an eye out for similar functionality in ergonomic mice.
  • Rechargeable VS Batteries: Some mice, like the Logitech MX Vertical, have rechargeable batteries that last for a few weeks on a single charge. Mice that use AA batteries, on the other hand, can last for months before needing a battery change. This is an issue of personal preference, of course.
  • Logitech Flow: The Logitech mice in this article work with Logitech Flow, which is software that makes two separate computers act like a multi-monitor setup. You can move your mouse across both computers without a hitch and even transfer files or copy-paste elements from one computer to another. It’s also compatible with most modern Logitech keyboards if you decide to buy both.

Best Overall: Logitech MX Vertical

A photo of the Logitech MX Vertical mouse.

Logitech’s MX Vertical mouse offers a stunning mix of ergonomics, style, and usability. Its intuitive design is easy to get accustomed to, and its accessible forward/back buttons and cursor speed switch ensure that you can quickly navigate the web without a hitch. Like other Logitech mice, the MX Vertical can connect to three computers at a time. It can also quickly switch between computers manually at the press of a button or automatically if you have Logitech Flow enabled.

Like most premium mice, the MX Vertical runs on a rechargeable battery that lasts for around two weeks. It pairs with your computer via Bluetooth or wireless dongle, but it can function as a wired mouse when connected to a computer via USB-C cable.

Best Overall

Logitech MX Vertical Wireless Mouse – Advanced Ergonomic Design Reduces Muscle Strain, Control and Move Content Between 3 Windows and Apple Computers (Bluetooth or USB), Rechargeable, Graphite

Read Review Geek's Full Review

Logitech's MX Vertical mouse brings ergonomics without sacrificing style and usability. It can connect to three devices at a time, it has a cursor speed switch, and its forward/back buttons are comfortable to use.

Another Favorite: Microsoft Sculpt Mouse

A photo of the Microsoft Sculpt mouse.

We’re big fans of the Microsoft Sculpt mouse, which sports an oddly comfortable blob-like design. It’s a fantastic ergonomic mouse for people who want the ergonomics of a vertical mouse without, you know, using a vertical mouse.

The sculpt has a Windows button mounted in its thumb rest, which quickly pulls up the Windows start menu. It also has a page-back button hidden toward the end of its thumb rest, but it doesn’t have a page-forward button. The sculpt connects to your computer over a wireless dongle and runs on two AA batteries.

Microsoft sells the Sculpt as a standalone mouse and as an ergonomic keyboard + mouse combo.

Another Favorite

Microsoft Sculpt Ergonomic Mouse, Black - Wireless Mouse for Natural Wrist Comfort with 4-Way Scroll Wheel for PC/Laptop/Desktop, works with Mac/Windows 8/10/11 Computers

The Microsoft Sculpt mouse encourages ergonomics without deviating too far from traditional mouse design. It's wireless, affordable, and comfortable to use.

Best Budget Option: iClever Vertical Mouse

A photo of the iClever Vertical Mouse

Want to replace your mouse without breaking the bank? The iClever Vertical mouse offers ergonomics and functionality that are comparable to the Logitech MX Vertical for under $20. Like the MX Vertical, the iClever has forward/back buttons and a cursor speed switch for easy, intuitive navigation. It connects to your computer over a wireless dongle and runs on AA batteries.

Unlike the MX Vertical mouse, the iClever cannot connect to multiple devices at a time.

Best Trackball Mouse: Kensington Orbit

A photo of the Kensington Orbit.

Ergonomics experts suggest using a finger-controlled trackball mouse to achieve the highest level of ergonomics and precision. The Kensington Orbit is, for the price, one of the best finger-controlled trackball mice that you can buy. It’s large enough to force your hand in an ergonomic position and has two comfortable (and customizable) buttons for navigating your computer. You can even customize the cursor speed of this trackball, or attach the included wrist rest for extra comfort.

The Kensington Orbit connects to your computer via USB cable and remains stationary during use. If you’d prefer to use a thumb-controlled trackball mouse with a more traditional feel, then the Logitech MX Ergo stands as a stunning (and expensive) alternative to the Kensington Orbit.

Best Trackball Mouse

Kensington Orbit Trackball Mouse with Scroll Ring (K72337US)

This trackball mouse offers superior ergonomics at a reasonable price. It takes some getting used to, but the learning curve is worth dealing with if you're serious about ergonomics.

For Traditional Mouse Fans: Logitech MX Master 3

A photo of the Logitech MX Master 3

The Logitech MX Master 3 is one of Review Geek‘s favorite mice. Everything about this mouse is customizable, from its forward/back buttons to its thumb-operated wheel. And while it doesn’t offer the superior ergonomics of a vertical or trackball mouse, it stands as a wonderful in-between option for people who want to use a traditional mouse without putting too much strain on their wrist.

Unlike other traditional-styled mice, the MX Master 3 is quite bulky and forces your hand into an ergonomic, yet comfortable position. It also has a very large thumb rest to encourage balance and precision—something that you rarely find in traditional mice.

Like the other Logitech mice mentioned in this article, the MX Master 3 can connect to three devices at a time and supports Logitech Flow. It runs on a rechargeable battery and can work via Bluetooth, wireless dongle, or USB-C cable. Logitech sells the MX Master 3 as a standalone mouse and a keyboard + mouse set.

If you’re looking for a traditional-styled mouse at a more affordable price, then the Microsoft Ergonomic Mouse stands as a decent alternative to the MX Master 3.

For Traditional Mouse Fans

Logitech MX Master 3 Advanced Wireless Mouse, Ultrafast Scrolling, Ergonomic, 4000 DPI, Customization, USB-C, Bluetooth, USB, Apple Mac, Microsoft PC Windows, Linux, iPad - Graphite

Read Review Geek's Full Review

The MX Master 3 sports a traditional style, yet it's incredibly ergonomic. Its large form-factor and thumb rest encourage you to use a straight wrist, and its customizable buttons and wheels are to die for.

Best for Gamers: Razer Basilisk V3

Top-down view of the Razer Basilisk V3 ergonomic gaming mouse with fun RGB lighting effect around it

Whether you regularly have lengthy gaming sessions or are just looking for a comfy mouse that’ll help prevent an overuse injury, the Razer Basilisk V3 is the go-to ergonomic gaming mouse. It feels super comfy in your hand and has an arched design that will support your palm and wrist all day. Plus, it features 11 programmable buttons for your preferred macros, and even includes its multi-function trigger, which you can use for essential actions.

The mouse features Razer’s HyperScroll Tilt Wheel so you can freely (and smoothly) whoosh through long web pages or menus. You can also toggle the tactile mode for a more traditional feel. The mouse also features the Razer Focus+ 26K DPI optical sensor that can handle intelligent tasks like asymmetric cut-off, error-free movement tracking, crisp response, and insane accuracy and precision whenever you click. And with its large, comfortable thumb rest, you can stay comfortable and in the zone, no matter what game you play.

Best for Gamers

Razer BasiliskV3

Read How-To Geek's Full Review

Hit targets, slay enemies, and stay in proper form with this ergonomic gamer-friendly pick from Razer.

Best for Left-Handed Users: Evoluent VerticalMouse 4 Left

Front of the Evoluent VML4L vertical ergonomic mouse for left-handed users

Because ergonomic mice usually have more of a sculpted design, it’s common for them to favor right-handed users and for there to be fewer options for ambidextrous and left-handed users. But if you’re left-handed, don’t worry—the Evoluent VerticalMouse 4 is a terrific pick for lefties!

Its vertical design avoids forearm twisting, and the gigantic thumb rest makes for an even comfier grip. With its top-mounted LEDs, you can see the mouse’s pointer speed at a glance. It also features six buttons you can use for action shortcuts, and you can manage it through the Evoluent Mouse Manager optional software.

Best for Left-Handed Users

Evoluent VerticalMouse 4 Left

Looking for a lefty-friendly ergonomic mouse? You'll love this comfy pick.

Andrew Heinzman Andrew Heinzman
Andrew is the News Editor for Review Geek, where he covers breaking stories and manages the news team. He joined Life Savvy Media as a freelance writer in 2018 and has experience in a number of topics, including mobile hardware, audio, and IoT. Read Full Bio »